新輔助放化療對(duì)中晚期食管鱗癌病理分期及預(yù)后的影響
食管腫瘤;新輔助放化療;病理分期;預(yù)后,曹秀峰,王和明,黃水清,朱斌,紀(jì)律,肖建,王山,吳必超,黃志華,朱海文,通訊作者:,Effectsofneoadjuvantradiochemotherapyonpathologicalstageandpr
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曹秀峰, 王和明, 黃水清, 朱斌, 紀(jì)律, 肖建, 南京醫(yī)科大學(xué)附屬南京第一醫(yī)院腫瘤中心 江蘇省南京市 210006
王山, 吳必超, 黃志華, 朱海文, 江蘇省鹽城市腫瘤醫(yī)院 江蘇省鹽城市 224002
曹秀峰, 胸外科主任醫(yī)師, 腫瘤學(xué)研究員, 外科學(xué)教授, 主要從事消化道腫瘤以手術(shù)為主的綜合治療及早診早治規(guī)范化模式研究.
通訊作者: 曹秀峰, 210006, 江蘇省南京市長(zhǎng)樂(lè)路68號(hào), 南京醫(yī)科大學(xué)附屬南京第一醫(yī)院腫瘤中心. cxf551101@sina.com
電話: 025-52271474
收稿日期: 2007-04-19 修回日期: 2007-07-23
Effects of neoadjuvant radiochemotherapy on pathological stage and prognosis of middle and advanced esophageal carcinoma
Xiu-Feng Cao, Shan Wang, Bi-Chao Wu, Zhi-Hua Huang, Hai-Wen Zhu, He-Ming Wang, Shui-Qing Huang, Bing Zhu, Lv Ji, Jian Xiao
Xiu-Feng Cao, He-Ming Wang, Shui-Qing Huang, Bing Zhu, Lv Ji, Jian Xiao, Oncology Center of Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing 210006, Jiangsu Province, China
Shan Wang, Bi-Chao Wu, Zhi-Hua Huang, Hai-Wen Zhu, Yancheng Tumor Hospital, Yancheng 224002, Jiangsu Province, China
Correspondence to: Xiu-Feng Cao, Oncology Center of Nanjing First Hospital Affiliated to Nanjing Medical University, 68 Changle Road, Nanjing 210006, Jiangsu Province, China. cxf551101@sina.com
Received: 2007-04-19 Revised: 2007-07-23
Abstract
AIM: To evaluate the effects of neoadjuvant radiochemotherapy on the pathological stage and prognosis of middle and advanced esophageal carcinoma.
METHODS: Between January 1991 and December 2000, 473 patients with middle and advanced esophageal carcinoma were randomly divided into four groups; neoadjuvant radiotherapy (n = 118), neoadjuvant chemotherapy (n = 119), neoadjuvant radiochemotherapy (n = 118) and control (surgery alone) (n = 118). The differences in resection rates, pathological stage, treatment-related complications and survival rates were statistically analyzed.
RESULTS: The data showed that the radical resection rate for patients in the radiotherapy, chemotherapy and radiochemotherapy groups was increased compared with that of the control group (97 ......
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