胃原發(fā)性淋巴瘤 16 例內鏡活檢及臨床病理特征分析
胃腫瘤;,淋巴瘤;內鏡活檢,,胃腫瘤;,淋巴瘤;內鏡活檢,胃原發(fā)性淋巴瘤16例內鏡活檢及臨床病理特征分析,1材料與方法,2結果,3討論,【參考文獻】
【摘要】 目的 探討胃原發(fā)性淋巴瘤黏膜活檢的病理診斷特點。方法 內鏡胃黏膜活檢標本和切除標本經(jīng)常規(guī)石蠟包埋切片、HE染色和SP法免疫組化染色后光鏡下觀察。結果 活檢組織中均呈現(xiàn)不同程度的異型淋巴細胞彌漫浸潤,腺體數(shù)量減少或完全消失;9例出現(xiàn)淋巴上皮病變,3例出現(xiàn)可疑淋巴上皮病變;10例伴有炎癥滲出壞死和組織擠壓損傷。結論 異型淋巴細胞彌漫浸潤是活檢診斷的主要特征;活檢組織中可能不出現(xiàn)淋巴上皮病變;常伴有其他組織學改變。【關鍵詞】 胃腫瘤; 淋巴瘤;內鏡活檢
Primary gastric lymphoma in endoscopic biopsied specimens: a pathological analysis of 16 cases
WANG Zhong-hua, ZHANG Yi-gui, LIU Lu-min,et al.
Department of Pathology, PLA Zhoushan Garrison Hospital,Zhoushan,Zhejiang 316000,China
【Abstract】 Objective To investigate the pathological characteristics of primary gastric lymphoma in endoscopic biopsied specimens. Methods All the tissue samples were 10% formalin-fixed, paraffin-embedded and stained with hematoxylin-eosin and SP immunohistochemistry.Results There were variable atypia, diffuse lymphoid cell infiltration with decrease or disappearance of the gland in the biopsied sample; The lymphoepithelial lesions were seen in 9 cases and suspected lymphoepithelial lesions in 3 cases; There were inflammatory necrosis and pressing tissues injury in 10 cases.Conclusion The main diagnostic characteristics of gastric lymphoma are variable atypia ......
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