視野和眼B型超聲檢查在甲狀腺相關(guān)性眼病診療中的臨床分析
甲狀腺相關(guān)性眼;視野;超聲,B型;眼,,],甲狀腺相關(guān)性眼;視野;超聲,B型;眼,[關(guān)鍵詞]甲狀腺相關(guān)性眼;視野;超聲,B型;眼,1資料與方法,2結(jié)果,3討論,[參考文獻]
[摘要] 目的 觀察視野和眼B超檢查在甲狀腺相關(guān)性眼病(TAO)的診斷和治療中的臨床價值。方法 對2000年1月~2006年1月在北京協(xié)和醫(yī)院確診并接受非手術(shù)治療(包括口服糖皮質(zhì)激素、放射治療)的40例TAO患者的66眼進行回顧性分析,分別比較患眼在治療前后的視野和眼外肌厚度的變化。應(yīng)用Octopus 101型自動視野計進行視野檢查,檢查采用TOP程序,59個位點,背景光4 asb,半暗室環(huán)境下進行;所有患者均用B超(Quantel Medical)測量眼外肌厚度。結(jié)果 40例患者的66眼均有不同程度的單條或多條眼外肌肉受累,采用不同的治療方法后,眼外肌的肥厚均有不同程度地好轉(zhuǎn),比較治療前后的雙眼上、下、內(nèi)直肌肌肉厚度的改變差異有明顯統(tǒng)計學意義(P<0.01); 視野結(jié)果顯示治療前后有明顯的改善,雙眼的平均敏感度(MS)、平均缺陷度(MD)和丟失方差(LV)的變化差異有明顯統(tǒng)計學意義(P<0.01)。結(jié)論 聯(lián)合視野和眼B超的檢查可以作為TAO的診斷、治療和預(yù)后隨診的常規(guī)檢查,同時能夠提供更為客觀和可靠的臨床依據(jù),有助于判斷TAO患者是否有視神經(jīng)的受累和評估TAO的臨床治療效果。[關(guān)鍵詞] 甲狀腺相關(guān)性眼。灰曇;超聲,B型;眼
Clinical observation of visual field test and ocular ultrasonic examination on the diagnosis and treatment of the thyroid associated ophthalmopathy
ZHONG Yong,SHI Wei,LIU Yu-hua,et al.
Department of Ophthalmology,Peking Union Medical College Hospital,Beijing 100730,China
[Abstract] Objective To evaluate the clinical significance of the visual field test and the ocular B-scan ultrasonic examination regarding to the diagnosis and treatment of the thyroid associated ophthalmopathy (TAO).Methods 40 cases (66 eyes) who were treated by steroids medication and radiotherapy were studied from January 2001 to January 2006 retrospectively.The visual field and thickness of the extra-ocular muscles were tested during pre-therapy and post-therapy.Results The extra-ocular muscles of 66 eyes showed a various enlargement.The medial,lateral,superior and inferior rectus of both eye presented a significant difference between in pre-therapy and post-therapy.In terms of the visual field test,the mean sensitivity (MS),mean defect (MD) and loss variance (LV) all were statistically significant difference before and after treatment.Conclusion The combination of visual field and ocular B-scan ultrasonic examination could be a routine test for the diagnosis and follow-up of the TAO patients,which may be of clinical significance to the evaluation of optic neuropathy and the outcome of therapy of the TAO. ......
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