超聲造影聯(lián)合補(bǔ)腎活血法治療輸卵管性不孕的臨床觀察(1)
摘要：目的探討超聲造影聯(lián)合補(bǔ)腎活血法診治輸卵管性不孕的臨床效果。方法將2015年6月—2016年6月于本院診治的輸卵管性不孕患者80例隨機(jī)分2組，對(duì)照組40例用輸卵管介入術(shù)治療，觀察組40例用過(guò)氧化碳酰胺超聲下通液+補(bǔ)腎活血大法治療；詳細(xì)記錄2組患者治療前后子宮內(nèi)膜厚度、E2水平變化情況、妊娠情況。結(jié)果觀察組子宮內(nèi)膜厚度及E2水平改善程度優(yōu)于對(duì)照組、妊娠情況優(yōu)于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論輸卵管性不孕患者選擇超聲造影+補(bǔ)腎活血法診治的效果較好，可充分改善患者治療后子宮內(nèi)膜厚度及E2水平，可獲得較高的妊娠率，值得臨床上廣泛應(yīng)用。
關(guān)鍵詞：超聲造影；補(bǔ)腎活血；輸卵管性不孕
中圖分類號(hào)：R271.14文獻(xiàn)標(biāo)志碼：B文章編號(hào)：1007-2349(2017)12-0023-03
【Abstract】Objective： To study the clinical effect of contrast-enhanced ultrasound combined with kidney-tonifying and blood activating method on diagnosis and treatment of tubal infertility. Methods： 80 patients who were diagnosed and treated in our hospital from June 2015 to June 2016 were randomly divided into two groups， 40 cases per group. The patients in the control group were treated with tubal intervention while the patients in the observation group were treated with carbamide peroxide ultrasonic fluid plus kidney-tonifying and blood activating method. The endometrial thickness， E2 level changes and pregnancy of the two groups before and after treatment were recorded in detail. Results： The improvement of endometrial thickness and E2 level in observation group was better than that in control group and the pregnancy was better than that of the control group. The difference was statistically significant (P<0.05). Conclusion： The diagnosis and treatment of tubal infertility patients by contrast-enhanced ultrasound and kidney-invigorating and blood-activating method are good， which can fully improve the thickness of endometrium and the level of E2 after treatment， and obtain higher pregnancy rate， worthy of wide application in clinic.
【Key words】contrast-enhanced ultrasound， kidney-invigorating and blood-activating method， tubal infertility
輸卵管因素導(dǎo)致的不孕約占整個(gè)不孕癥人群45%～55%，是引起女性不孕的首要原因[1]。急慢性盆腔炎等則是導(dǎo)致輸卵管性不孕的常見(jiàn)原因，可引起輸卵管阻塞、蠕動(dòng)能力減弱而致不孕。輸卵管性不孕是一種相對(duì)不孕，且大多為繼發(fā)性不孕，通過(guò)治療可以獲得妊娠。針對(duì)輸卵管性不孕的治療，常根據(jù)輸卵管阻塞部位和程度的不同采用輸卵管通液、宮腔鏡下輸卵管插管通液、宮腹腔鏡手術(shù)以及輔助生育技術(shù)等。社會(huì)不斷進(jìn)步，輸卵管炎性不孕的臨床發(fā)病率卻逐年上升。在我國(guó)經(jīng)濟(jì)迅速發(fā)展、計(jì)劃生育不斷調(diào)整的今天，生育成為了大多數(shù)家庭關(guān)注的重點(diǎn)。面對(duì)輸卵管炎性不孕的高發(fā)病率，面對(duì)輸卵管性不孕，如何選擇一種簡(jiǎn)便、易行、療效可靠的診治方法，至關(guān)重要。本文旨右探討過(guò)氧化碳酰胺超聲下通液加補(bǔ)腎活血大法診治輸卵管性不孕的療效�，F(xiàn)將結(jié)果報(bào)道如下。
1資料與方法
1.1一般資料將2015年6月—2016年6月于本院診治的輸卵管性不孕患者80例隨機(jī)分為對(duì)照組與觀察組。對(duì)照組40例患者中：年齡24～38歲，平均年齡為(28.16±3.42)歲；病程2～3.5 a，平均病程為(3.14±0.31)a；原發(fā)性17例、繼發(fā)性23例。觀察組40例患者中：年齡23～35歲，平均年齡為(27.01±3.17)歲；病程2.3～3.5 a，平均病程為(3.09±0.25)a；原發(fā)性15例、繼發(fā)性25例；2組患者一般資料比較，差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)，具有可比性。
1.2治療方法
1.2.1對(duì)照組本組用輸卵管介入術(shù)治療：選擇COOK公司生產(chǎn)的9F/5F/3F導(dǎo)管、0.015導(dǎo)絲各1個(gè)，用Ziehm8000 X光機(jī)為患者診療；為患者用76%泛影葡胺造影，確定病變位置后經(jīng)9F導(dǎo)管將5F導(dǎo)管、白泥鰍導(dǎo)絲插入到間質(zhì)處取出導(dǎo)絲，再經(jīng)5F導(dǎo)管插進(jìn)3F導(dǎo)管+0.015導(dǎo)絲，待交替前行穩(wěn)定后取出導(dǎo)絲，以3F導(dǎo)管將造影劑注入，造影劑均勻彌散于盆腔時(shí)則提示復(fù)通成功，再經(jīng)3F導(dǎo)管將香丹注射液(20 mL)注入；診治后首次月經(jīng)干凈后3～7 d內(nèi)做輸卵管介入術(shù)，下個(gè)月經(jīng)周期時(shí)做宮腔輸卵管通液術(shù)1次，并注入香丹注射液(40 mL)。, http://www.www.srpcoatings.com(牛紅萍 詹興秀 周曉娜)
關(guān)鍵詞：超聲造影；補(bǔ)腎活血；輸卵管性不孕
中圖分類號(hào)：R271.14文獻(xiàn)標(biāo)志碼：B文章編號(hào)：1007-2349(2017)12-0023-03
【Abstract】Objective： To study the clinical effect of contrast-enhanced ultrasound combined with kidney-tonifying and blood activating method on diagnosis and treatment of tubal infertility. Methods： 80 patients who were diagnosed and treated in our hospital from June 2015 to June 2016 were randomly divided into two groups， 40 cases per group. The patients in the control group were treated with tubal intervention while the patients in the observation group were treated with carbamide peroxide ultrasonic fluid plus kidney-tonifying and blood activating method. The endometrial thickness， E2 level changes and pregnancy of the two groups before and after treatment were recorded in detail. Results： The improvement of endometrial thickness and E2 level in observation group was better than that in control group and the pregnancy was better than that of the control group. The difference was statistically significant (P<0.05). Conclusion： The diagnosis and treatment of tubal infertility patients by contrast-enhanced ultrasound and kidney-invigorating and blood-activating method are good， which can fully improve the thickness of endometrium and the level of E2 after treatment， and obtain higher pregnancy rate， worthy of wide application in clinic.
【Key words】contrast-enhanced ultrasound， kidney-invigorating and blood-activating method， tubal infertility
輸卵管因素導(dǎo)致的不孕約占整個(gè)不孕癥人群45%～55%，是引起女性不孕的首要原因[1]。急慢性盆腔炎等則是導(dǎo)致輸卵管性不孕的常見(jiàn)原因，可引起輸卵管阻塞、蠕動(dòng)能力減弱而致不孕。輸卵管性不孕是一種相對(duì)不孕，且大多為繼發(fā)性不孕，通過(guò)治療可以獲得妊娠。針對(duì)輸卵管性不孕的治療，常根據(jù)輸卵管阻塞部位和程度的不同采用輸卵管通液、宮腔鏡下輸卵管插管通液、宮腹腔鏡手術(shù)以及輔助生育技術(shù)等。社會(huì)不斷進(jìn)步，輸卵管炎性不孕的臨床發(fā)病率卻逐年上升。在我國(guó)經(jīng)濟(jì)迅速發(fā)展、計(jì)劃生育不斷調(diào)整的今天，生育成為了大多數(shù)家庭關(guān)注的重點(diǎn)。面對(duì)輸卵管炎性不孕的高發(fā)病率，面對(duì)輸卵管性不孕，如何選擇一種簡(jiǎn)便、易行、療效可靠的診治方法，至關(guān)重要。本文旨右探討過(guò)氧化碳酰胺超聲下通液加補(bǔ)腎活血大法診治輸卵管性不孕的療效�，F(xiàn)將結(jié)果報(bào)道如下。
1資料與方法
1.1一般資料將2015年6月—2016年6月于本院診治的輸卵管性不孕患者80例隨機(jī)分為對(duì)照組與觀察組。對(duì)照組40例患者中：年齡24～38歲，平均年齡為(28.16±3.42)歲；病程2～3.5 a，平均病程為(3.14±0.31)a；原發(fā)性17例、繼發(fā)性23例。觀察組40例患者中：年齡23～35歲，平均年齡為(27.01±3.17)歲；病程2.3～3.5 a，平均病程為(3.09±0.25)a；原發(fā)性15例、繼發(fā)性25例；2組患者一般資料比較，差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)，具有可比性。
1.2治療方法
1.2.1對(duì)照組本組用輸卵管介入術(shù)治療：選擇COOK公司生產(chǎn)的9F/5F/3F導(dǎo)管、0.015導(dǎo)絲各1個(gè)，用Ziehm8000 X光機(jī)為患者診療；為患者用76%泛影葡胺造影，確定病變位置后經(jīng)9F導(dǎo)管將5F導(dǎo)管、白泥鰍導(dǎo)絲插入到間質(zhì)處取出導(dǎo)絲，再經(jīng)5F導(dǎo)管插進(jìn)3F導(dǎo)管+0.015導(dǎo)絲，待交替前行穩(wěn)定后取出導(dǎo)絲，以3F導(dǎo)管將造影劑注入，造影劑均勻彌散于盆腔時(shí)則提示復(fù)通成功，再經(jīng)3F導(dǎo)管將香丹注射液(20 mL)注入；診治后首次月經(jīng)干凈后3～7 d內(nèi)做輸卵管介入術(shù)，下個(gè)月經(jīng)周期時(shí)做宮腔輸卵管通液術(shù)1次，并注入香丹注射液(40 mL)。, http://www.www.srpcoatings.com(牛紅萍 詹興秀 周曉娜)
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