中醫(yī)外治MHD患者皮膚瘙癢臨床研究(1)
摘要 目的：探討以“養(yǎng)血活血、利濕化濁”立法中醫(yī)辨證外用治療MHD患者皮膚瘙癢的臨床療效。方法：選取2015年1月至2016年6月就診的MHD皮膚瘙癢患者64例，隨機(jī)分為治療組和對照組各32例，對照組給予低磷飲食、基礎(chǔ)治療、血液透析每周3次，治療組在對照組基礎(chǔ)上以養(yǎng)血活血、利濕化濁中藥辨證外治，觀察2組治療前后臨床總有效率、皮膚瘙癢評分、血生化等指標(biāo)變化。結(jié)果：臨床總有效率比較：治療組為93.7%，對照組為68.7%，兩者統(tǒng)計學(xué)有統(tǒng)計學(xué)意義(P<0.01)；2組皮膚瘙癢評分與血生化比較：治療組治療后皮膚瘙癢評分、血BUN和IP水平與治療前比較均有顯著降低(P<0.05)，與對照組治療后比較統(tǒng)計學(xué)也均有顯著下降(P<0.05)；2組治療后血Scr、CA、PTH比較明顯變化(P<0.05)。結(jié)論：以“養(yǎng)血活血、利濕化濁”立法中醫(yī)辨證外治，不僅可緩解MHD患者皮膚瘙癢，還有效降低了血BUN、IP水平，值得臨床推廣應(yīng)用。
關(guān)鍵詞 中醫(yī)外治；MHD；皮膚瘙癢
Abstract Objective： To discuss the clinical effect on skin pruritus in Maintenance hemodialysis (MHD)patients with external treatment of Traditional Chinese Medicine (TCM )by means of “nourishing and activating blood， removing dampness and turbidity”.Methods： A total of 64 cases of MHD patients with skin pruritus treated during January 2015 to June 2016 were selected. They were randomly divided into treatment group and control group with 32 cases in each. The control group was given low-phosphorus diet with basic treatment and Hemodialysis three times a week. On the basis of the control group， external treatment was added to another group upon sysndrome differentiation with traditional Chinese herbs or prescriptions functioning as nourishing and activating blood， and removing dampness and turbid The total clinical effective rate， skin pruritus score and blood biochemical data were observed before and after the treatment. Results： The total clinical effective rate of treatment group was 93.7%， and control group was 68.7%. There was statistically significant difference between the two groups (P<0.01)； The comparison of skin pruritus score and blood biochemical data in the two groups： the skin pruritus score， levels of blood urea nitrogen and serum phosphorus of the treatment group were significantly decreased(P<0.05)； there was also significant reduction compared with the control group(P<0.05)； The two groups underwent obviously changes in the levels of serum creatinine、Serum calcium and serum parathyroid hormone (P<0.05). Conclusion： With the strategy of “nourishing and activating blood， removing dampness and turbid”based upon TCM syndrome differentiation， not only can skin pruritus be relieved from patients with MHD， but also levels of Blood urea nitrogen and Serum phosphorus are effectively reduced， which is worthy of clinical application.
Key Words Eexternal Treatment of Traditional Chinese Medicine； Maintenance Hemodialysis； Skin Pruritus
中圖分類號：R242文獻(xiàn)標(biāo)識碼：Adoi：10.3969/j.issn.1673-7202.2017.05.020, http://www.www.srpcoatings.com(邊紅萍 張勝榮 王小琴)
關(guān)鍵詞 中醫(yī)外治；MHD；皮膚瘙癢
Abstract Objective： To discuss the clinical effect on skin pruritus in Maintenance hemodialysis (MHD)patients with external treatment of Traditional Chinese Medicine (TCM )by means of “nourishing and activating blood， removing dampness and turbidity”.Methods： A total of 64 cases of MHD patients with skin pruritus treated during January 2015 to June 2016 were selected. They were randomly divided into treatment group and control group with 32 cases in each. The control group was given low-phosphorus diet with basic treatment and Hemodialysis three times a week. On the basis of the control group， external treatment was added to another group upon sysndrome differentiation with traditional Chinese herbs or prescriptions functioning as nourishing and activating blood， and removing dampness and turbid The total clinical effective rate， skin pruritus score and blood biochemical data were observed before and after the treatment. Results： The total clinical effective rate of treatment group was 93.7%， and control group was 68.7%. There was statistically significant difference between the two groups (P<0.01)； The comparison of skin pruritus score and blood biochemical data in the two groups： the skin pruritus score， levels of blood urea nitrogen and serum phosphorus of the treatment group were significantly decreased(P<0.05)； there was also significant reduction compared with the control group(P<0.05)； The two groups underwent obviously changes in the levels of serum creatinine、Serum calcium and serum parathyroid hormone (P<0.05). Conclusion： With the strategy of “nourishing and activating blood， removing dampness and turbid”based upon TCM syndrome differentiation， not only can skin pruritus be relieved from patients with MHD， but also levels of Blood urea nitrogen and Serum phosphorus are effectively reduced， which is worthy of clinical application.
Key Words Eexternal Treatment of Traditional Chinese Medicine； Maintenance Hemodialysis； Skin Pruritus
中圖分類號：R242文獻(xiàn)標(biāo)識碼：Adoi：10.3969/j.issn.1673-7202.2017.05.020, http://www.www.srpcoatings.com(邊紅萍 張勝榮 王小琴)
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