免疫抑制作用下雷公藤藤多甙片治療IgA腎病效果觀察(1)
摘要 目的:探討免疫抑制作用下雷公藤藤多甙片治療IgA腎病的治療效果。方法:選取2015年12月至2016年12月河南省中醫(yī)藥研究院附屬醫(yī)院收治的IgA腎病患者60例,根據(jù)治療方式的不同隨機(jī)分為觀察組和對(duì)照組,每組30例,對(duì)照組采用常規(guī)方法進(jìn)行治療,觀察組在常規(guī)治療的基礎(chǔ)上給予具有免疫抑制作用的雷公藤多甙片進(jìn)行治療,比較2組患者治療情況。結(jié)果:觀察組和對(duì)照組經(jīng)過(guò)治療后,尿紅細(xì)胞相位計(jì)數(shù)、24 h尿蛋白定量、血壓、血清肌酐4項(xiàng)指標(biāo)均比治療前有所改善,觀察組改善效果比對(duì)照組更加顯著,差異有統(tǒng)計(jì)學(xué)意義( P <0.05);2組患者經(jīng)過(guò)治療后,對(duì)照組的治療有效率為60%,對(duì)照組的治療有效率為90%,差異有統(tǒng)計(jì)學(xué)意義( P <0.05)。結(jié)論:臨床上采用免疫抑制作用的雷公藤多甙片治療IgA腎病可以取得顯著的療效,可以使用IgA腎病患者的臨床癥狀得到顯著的改善,具有可靠、安全等優(yōu)點(diǎn),值得在臨床上推廣應(yīng)用。
關(guān)鍵詞 免疫抑制作用;常規(guī)治療;雷公藤多甙片;IgA腎病;尿紅細(xì)胞相位計(jì)數(shù);血壓;血清肌酐;療效
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Effects Observation of the Action of Tripterygium Wilfordii Stendardo Glucoside Tablets in the Treatment of IgA Nephropathy under Immunosuppression
Yu Guojun,Luo Fang,Cheng Xin,Hu Jiangping,Zuo Fang
(Department of Nephropathy,the Affiliated Hospital of Traditional Chinese Medicine Research Institute of Henan Province,Zhengzhou 450000,China)
Abstract Objective: To evaluate the immunosuppressive effects of tripterygium wilfordii rattan glucoside piece with the curative effect of treatment of IgA nephropathy. Methods: From December 2015 to December 2016,a total of 60 patients with IgA nephropathy in the Affiliated Hospital of Traditional Chinese Medicine Research Institute of Henan Province were divided into observation group and control group with 30 cases in each group.The control group was treated with the conventional methods,while the observation group was given tripterygium wilfordii glycoside tablets with immunosuppressive effects on the basis of conventional treatment.the treatment of two groups was compared. Results: After treatment,the 24 h urine red blood cell phase counting,urine protein,blood pressure,serum creatinine quantitative of the observation group and control group were improved than before treatment.The observation group was improved more significantly than the control group,with statistically significant difference ( P <0.05).After treatment,the effective rate of the control group was 60%,and the control group was 90%,with statistically significant difference ( P <0.05). Conclusion: Clinical use of the tripterygium wilfordii glucoside tablets with the immunosuppressive effect in the treatment of IgA nephropathy can be achieved remarkable curative effect,and it can significantly improve the clinical symptoms of IgA nephropathy patients,and has the advantages of reliable,safe and worthy of popularization and application in clinic.
Key Words Immunosuppressive effect; Routine treatment; Tripterygium wilfordii multi glycoside tablet; IgA nephropathy; Urine red cell phase count; Blood pressure; Serum creatinine; Therapeutic effect, 百拇醫(yī)藥(于國(guó)俊 羅方 程新 胡江平 左芳)
關(guān)鍵詞 免疫抑制作用;常規(guī)治療;雷公藤多甙片;IgA腎病;尿紅細(xì)胞相位計(jì)數(shù);血壓;血清肌酐;療效
, http://www.www.srpcoatings.com
Effects Observation of the Action of Tripterygium Wilfordii Stendardo Glucoside Tablets in the Treatment of IgA Nephropathy under Immunosuppression
Yu Guojun,Luo Fang,Cheng Xin,Hu Jiangping,Zuo Fang
(Department of Nephropathy,the Affiliated Hospital of Traditional Chinese Medicine Research Institute of Henan Province,Zhengzhou 450000,China)
Abstract Objective: To evaluate the immunosuppressive effects of tripterygium wilfordii rattan glucoside piece with the curative effect of treatment of IgA nephropathy. Methods: From December 2015 to December 2016,a total of 60 patients with IgA nephropathy in the Affiliated Hospital of Traditional Chinese Medicine Research Institute of Henan Province were divided into observation group and control group with 30 cases in each group.The control group was treated with the conventional methods,while the observation group was given tripterygium wilfordii glycoside tablets with immunosuppressive effects on the basis of conventional treatment.the treatment of two groups was compared. Results: After treatment,the 24 h urine red blood cell phase counting,urine protein,blood pressure,serum creatinine quantitative of the observation group and control group were improved than before treatment.The observation group was improved more significantly than the control group,with statistically significant difference ( P <0.05).After treatment,the effective rate of the control group was 60%,and the control group was 90%,with statistically significant difference ( P <0.05). Conclusion: Clinical use of the tripterygium wilfordii glucoside tablets with the immunosuppressive effect in the treatment of IgA nephropathy can be achieved remarkable curative effect,and it can significantly improve the clinical symptoms of IgA nephropathy patients,and has the advantages of reliable,safe and worthy of popularization and application in clinic.
Key Words Immunosuppressive effect; Routine treatment; Tripterygium wilfordii multi glycoside tablet; IgA nephropathy; Urine red cell phase count; Blood pressure; Serum creatinine; Therapeutic effect, 百拇醫(yī)藥(于國(guó)俊 羅方 程新 胡江平 左芳)
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