血液灌流治療有機磷中毒的臨床研究(1)
 |
| 第1頁 |
參見附件(1351KB，2頁)。
[摘要] 目的：探討血液灌流治療急性有機磷農(nóng)藥中毒的臨床療效。方法：75例有機磷農(nóng)藥中毒患者，按入院后接受血液灌流(HP)或未接受血液灌流分為灌注組(HP組)38例和非灌注組(非HP組)37例，中毒患者送入本院后均按常規(guī)給予洗胃，及阿托品、解磷定治療和對癥支持治療，HP組加用血液灌流治療，觀察兩組患者治愈率、阿托品用量、意識恢復情況、膽堿酯酶活力和中間綜合征(IMS)發(fā)生率情況。結(jié)果：HP組38例全部治愈，發(fā)生IMS 1例。對照組37例治愈32例，治愈率為86.5%，其中5例死于呼吸衰竭，其中發(fā)生中間綜合征5例。兩組間意識恢復時間、阿托品所需總量、膽堿酯酶恢復時間比較，差異有統(tǒng)計學意義(P<0.05)。結(jié)論：血液灌流治療急性有機磷農(nóng)藥中毒的臨床療效顯著，可促進患者的意識恢復、減少阿托品的總用量、提高治愈率，值得臨床推廣應(yīng)用。
[關(guān)鍵詞] 有機磷農(nóng)藥中毒；血液灌流；臨床療效
[中圖分類號] R139+.3 [文獻標識碼]A [文章編號]1674-4721(2010)10(c)-017-02
Hemoperfusion clinical study of organophosphate poisoning
CHAO Jun， SONG Ying
(Department of Nephrology, Affiliated Hospital of Jiangsu University, Jiangsu Province, Zhenjiang 212001, China)
[Abstract] Objective: To evaluate the blood perfusion treatment of acute organophosphorus pesticide poisoning clinical efficacy. Methods: 75 patients with organophosphate poisoning patients, by admission, blood perfusion(HP) or a blood perfusion into perfusion group(HP group) 38 cases and non-perfusion group(non-HP group) 37 cases of poisoning patients admitted according to our hospital routinely given after gastric lavage and atropine, pralidoxime treatment and symptomatic and supportive treatment, HP group were treated with hemoperfusion, the cure rate were observed, the dosage of atropine, recovery of consciousness, choline esterase activity and the incidence of intermediate syndrome cases. Results: HP group, 38 patients were cured, the occurrence of IMS total of 1 case. The control group of 37 patients and 32 cases were cured, the cure rate was 86.5%, of which 5 patients died of respiratory failure. Occurrence of intermediate syndrome in which 5 cases. Consciousness recovery time between the two groups, the total required atropine and cholinesterase recovery time, the difference was statistically significant(P<0.05). Conclusion: Hemoperfusion treatment of acute organophosphorus pesticide poisoning and the clinical effect is significant, can promote patient awareness of recovery and reduce the total amount of atropine to improve the cure rate, is worthy of clinical application.
[Key words] Organic phosphorus pesticide poisoning; Blood perfusion; Clinical efficacy
有機磷農(nóng)藥中毒(AOPP)是急救醫(yī)學中常見的急危重癥之一 ......
您現(xiàn)在查看是摘要介紹頁，詳見PDF附件(1351KB，2頁)。