貝那普利聯(lián)合纈沙坦治療糖尿病腎病的臨床觀察(1)
![]() |
| 第1頁 |
參見附件(2063KB,2頁)。
[摘要] 目的:探討貝那普利聯(lián)合纈沙坦治療糖尿病腎病的臨床療效。方法:將本院收集的81例糖尿病腎、羝诨颊唠S機(jī)分成3組各27例,治療組接受貝那普利和纈沙坦聯(lián)合治療,對照組分別接受貝那普利、纈沙坦單獨(dú)治療。觀察并記錄治療前后血壓、24 h尿蛋白定量、血尿素氮(BUN)、血肌酐(Scr)、血鉀及血糖等指標(biāo)的變化。結(jié)果:治療12周后,各組治療前后血壓及24 h尿蛋白定量均顯著下降(P<0.05),且治療組明顯優(yōu)于對照組, 差異具有統(tǒng)計(jì)學(xué)意義(P<0.01)。結(jié)論:貝那普利聯(lián)合纈沙坦治療糖尿病腎病可明顯降低尿蛋白,控制血壓,提高療效。
[關(guān)鍵詞] 糖尿病腎;貝那普利;纈沙坦;臨床觀察
[中圖分類號] R587.2 [文獻(xiàn)標(biāo)識碼]B[文章編號]1674-4721(2011)05(c)-047-02
Clinical observation of the combination of benazepril and valsartan in the treatment of diabetic nephropathy
LI Jinshan1, WANG Jiaci2
1.Department of Nephrology, Chinese Medicine Hospital in Zhongshan City, Guangdong Province, Zhongshan 528400, China; 2.Comprehensive Sections, Chinese Medicine Hospital in Zhongshan City, Guangdong Province, Zhongshan 528400, China
[Abstract] Objective: To investigate the clinical efficacy of the combination of benazepril andvalsartan in the treatment of diabetic nephropathy. Methods: Collected 81 patients with diabetic nephropathy in Ⅳ phase in our hospital, who were randomly divided into three groups, each group had 27 cases, the treatment group complied with the combination of benazepril and valsartan, the control group respectively treated with benazepril and valsartan. Observed and recorded the blood pressure, 24 hours of urinary protein quantitative, blood urea nitrogen (BUN), creatinine (Scr), blood potassium and blood glucose etc. various changes in the indicators before and after the treatment. Results: After the treatment of 12 weeks, blood pressure and 24 hours of urinary protein quantitative in each group declined significantly (P<0.05), and the treatment group was better than the control groups, the difference had statistics significance (P<0.05). Conclusion: Combination of benazepril and valsartan on treating diabetic nephropathy can obviously decrease urinary protein, control blood pressure, enhance the curative effect.
[Key words] Diabetic nephropathy; Benazepril; Valsartan; Clinical observation
糖尿病腎病(diabetic nephropathy,DN)為臨床常見疾病,是目前導(dǎo)致終末期腎衰竭的最主要疾病[1]。本院運(yùn)用貝那普利和纈沙坦單獨(dú)或聯(lián)合治療糖尿病腎病患者81例,并對其進(jìn)行對比觀察,應(yīng)用貝那普利聯(lián)合纈沙坦治療糖尿病腎病效果顯著 ......
您現(xiàn)在查看是摘要介紹頁,詳見PDF附件(2063KB,2頁)。
