地佐辛術(shù)前給藥對(duì)全身麻醉患者蘇醒期躁動(dòng)和應(yīng)激反應(yīng)的影響(1)
[摘要] 目的 分析地佐辛術(shù)前給藥對(duì)全身麻醉患者蘇醒期躁動(dòng)和應(yīng)激反應(yīng)的影響。 方法 隨機(jī)抽取本院2012年3月～2014年3月收治的擇期接受腹腔鏡手術(shù)治療的80例患者作為研究對(duì)象，按照隨機(jī)對(duì)照法將其分為對(duì)照組與觀察組，每組40例。觀察組給予地佐辛術(shù)前給藥，對(duì)照組術(shù)前給予生理鹽水，采取躁動(dòng)評(píng)分及鎮(zhèn)靜評(píng)分量表評(píng)估兩組患者蘇醒期躁動(dòng)及應(yīng)激反應(yīng)發(fā)生情況，記錄患者的蘇醒時(shí)間。 結(jié)果 觀察組躁動(dòng)評(píng)級(jí)Ⅰ級(jí)38例，Ⅱ級(jí)2例，躁動(dòng)發(fā)生率為5.0%，明顯低于對(duì)照組的35.0%(P<0.05)。觀察組的蘇醒時(shí)間為(10.2±2.5)min，拔管時(shí)間為(13.2±3.4)min，均短于對(duì)照組，且觀察組的鎮(zhèn)靜評(píng)分為(2.7±0.2)分，明顯高于對(duì)照組，疼痛評(píng)分為(1.4±0.3)分，顯著低于對(duì)照組(P<0.05)。拔管時(shí)，觀察組的MAP為(86.0±13.3)mm Hg，血壓穩(wěn)定情況明顯優(yōu)于對(duì)照組，且其心率為(78.0±11.3)/min，穩(wěn)定情況優(yōu)于對(duì)照組(P<0.05)。 結(jié)論 采用地佐辛術(shù)前鎮(zhèn)痛處理方案可降低拔管期患者躁動(dòng)發(fā)生率，降低術(shù)后不良反應(yīng)發(fā)生率，鎮(zhèn)痛效果佳，安全性高，值得推廣應(yīng)用。
[關(guān)鍵詞] 地佐辛；麻醉；躁動(dòng)；應(yīng)激反應(yīng)；不良反應(yīng)
[中圖分類(lèi)號(hào)] R614.2+4 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-4721(2015)05(b)-0105-03
Impact of pre-operative administration of dezocine on emergence agitation and stress response for patients under general anesthesia
LI Wen-bing LI An-xue CAI Yun-liang▲ ZHU Hong
Department of Anesthesiology，People′s Hospital of Longgang District in Shenzhen City，Shenzhen 518172，China
[Abstract] Objective To analyze the impact of pre-operative administration of dezocine on emergence agitation and stress response for patients under general anesthesia. Methods 80 patients received selective laparoscopic surgery admitted into our hospital from March 2012 to March 2014 were randomly selected as research subjects.They were randomly divided into control group (n=40) and observation group (n=40) according to the randomized control method.Observation group was given pre-operative dezocine，and control group was given saline before surgery.Sedation and agitation score scale was applied to evaluate condition of emergence agitation and stress response in two groups，and patients′ recovery time was recorded. Results In observation group，38 patients were rated agitation level Ⅰ，and 2 patients were rated level Ⅱ.The incidence rate of agitation (5.0%) was significantly lower than that of in control group (35.0%) (P<0.05)；the emergence time in observation group [ (10.2±2.5) min]and extubating time [ (13.2±3.4) min] was shorter than that of control group respectively.Sedation score in observation group [(2.7±0.2) points] was significantly higher than that in control group.Pain score in observation group [ (1.4±0.3) points] was significantly lower than that in control group (P<0.05).Upon extubating，MAP in observation group was (86.0±13.3) mm Hg，and the blood pressure stability was significantly better than that in control group ahile the heart rate in observation group was (78.0±11.3) times every minute，and the stability of heart rate was also better than that in control group (P<0.05). Conclusion Pre-operative analgesia treatment scheme of dezocine before surgery helps reduce the incidence rate of agitation during extubating period in patients and lower the incidence rate of adverse effect.It has a favorable effect of analgesia and high safety，which is worthy of promotion and application. (李文兵 李安學(xué) 蔡云亮 朱紅)
[關(guān)鍵詞] 地佐辛；麻醉；躁動(dòng)；應(yīng)激反應(yīng)；不良反應(yīng)
[中圖分類(lèi)號(hào)] R614.2+4 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-4721(2015)05(b)-0105-03
Impact of pre-operative administration of dezocine on emergence agitation and stress response for patients under general anesthesia
LI Wen-bing LI An-xue CAI Yun-liang▲ ZHU Hong
Department of Anesthesiology，People′s Hospital of Longgang District in Shenzhen City，Shenzhen 518172，China
[Abstract] Objective To analyze the impact of pre-operative administration of dezocine on emergence agitation and stress response for patients under general anesthesia. Methods 80 patients received selective laparoscopic surgery admitted into our hospital from March 2012 to March 2014 were randomly selected as research subjects.They were randomly divided into control group (n=40) and observation group (n=40) according to the randomized control method.Observation group was given pre-operative dezocine，and control group was given saline before surgery.Sedation and agitation score scale was applied to evaluate condition of emergence agitation and stress response in two groups，and patients′ recovery time was recorded. Results In observation group，38 patients were rated agitation level Ⅰ，and 2 patients were rated level Ⅱ.The incidence rate of agitation (5.0%) was significantly lower than that of in control group (35.0%) (P<0.05)；the emergence time in observation group [ (10.2±2.5) min]and extubating time [ (13.2±3.4) min] was shorter than that of control group respectively.Sedation score in observation group [(2.7±0.2) points] was significantly higher than that in control group.Pain score in observation group [ (1.4±0.3) points] was significantly lower than that in control group (P<0.05).Upon extubating，MAP in observation group was (86.0±13.3) mm Hg，and the blood pressure stability was significantly better than that in control group ahile the heart rate in observation group was (78.0±11.3) times every minute，and the stability of heart rate was also better than that in control group (P<0.05). Conclusion Pre-operative analgesia treatment scheme of dezocine before surgery helps reduce the incidence rate of agitation during extubating period in patients and lower the incidence rate of adverse effect.It has a favorable effect of analgesia and high safety，which is worthy of promotion and application. (李文兵 李安學(xué) 蔡云亮 朱紅)