三氧化二砷聯(lián)合化療治療急性早幼粒細(xì)胞白血病血清血脂變化規(guī)律及不良反應(yīng)(1)
[摘要]目的 探討三氧化二砷治療急性早幼粒細(xì)胞白血病化療所引起的血清血脂變化、不良反應(yīng)。方法 從2005年4月~2015年3月本院內(nèi)科收治的白血病患者中選出64例急性早幼粒細(xì)胞白血病者,分析其在化療中聯(lián)合應(yīng)用三氧化二砷治療后血清總膽固醇(TC)、血清三酰甘油(TG)的變化及出現(xiàn)的不良反應(yīng)和生存率和復(fù)發(fā)率。結(jié)果 治療3個療程,患者TC和TG指標(biāo)均呈逐漸升高趨勢,差異有統(tǒng)計學(xué)意義(P<0.05)。不良反應(yīng)以消化系統(tǒng)反應(yīng)為主,骨髓抑制和肝腎功能損害最為嚴(yán)重。其治療后6、12、18個月的生存率分別為96.77%、91.94%、85.48%,復(fù)發(fā)率分別為9.68%、6.45%、4.84%。結(jié)論 三氧化二砷和化療聯(lián)合治療急性早幼粒細(xì)胞白血病血清血脂升高,不良反應(yīng)類型繁多。
[關(guān)鍵詞]三氧化二砷;化療;白血。谎逖;不良反應(yīng)
[中圖分類號] R733.71 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-4721(2017)03(b)-0034-03
[Abstract]Objective To study the changes of serum lipids and adverse reaction triggered by Arsenic Trioxide in acute promyelocytic leukemia with the combination of chemotherapy.Methods A total of 64 patients with acute promyelocytic leukemia in our department of internal medicine in our hospital from April 2005 to March 2015 were selected.The levels of serum total cholesterol (TC) and triacylglycerol (TG) ......
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[關(guān)鍵詞]三氧化二砷;化療;白血。谎逖;不良反應(yīng)
[中圖分類號] R733.71 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-4721(2017)03(b)-0034-03
[Abstract]Objective To study the changes of serum lipids and adverse reaction triggered by Arsenic Trioxide in acute promyelocytic leukemia with the combination of chemotherapy.Methods A total of 64 patients with acute promyelocytic leukemia in our department of internal medicine in our hospital from April 2005 to March 2015 were selected.The levels of serum total cholesterol (TC) and triacylglycerol (TG) ......
您現(xiàn)在查看是摘要頁,全文長 3583 字符。