腰椎間盤突出引發(fā)疼痛的機制研究進展(1)
腰椎間盤突出引發(fā)疼痛的機制研究進展,腰椎間盤突出癥,疼痛機制,腰痛
[摘要]腰椎間盤突出癥是骨傷科的常見病和多發(fā)病,對患者、家庭及社會均帶來沉重的負擔(dān),腰腿痛是腰椎間盤突出癥的最主要癥狀。目前,在腰椎間盤突出癥疼痛的發(fā)病機制方面,比較公認的有機械壓迫、神經(jīng)根炎性刺激、細胞凋亡、椎間盤自身免疫反應(yīng)及生物力學(xué)機制5種觀點,諸多發(fā)病機制仍然不能很好地詮釋腰椎間盤突出引起疼痛的根本原因,故尚待進一步深入研究和探討。本文就腰椎間盤突出引發(fā)疼痛的機制研究進展進行綜述。[關(guān)鍵詞]腰椎間盤突出癥;疼痛機制;研究進展;腰痛
[中圖分類號] R681.5+5 [文獻標(biāo)識碼] A [文章編號] 1674-4721(2018)12(c)-0017-05
[Abstract] Lumbar intervertebral disc herniation is a common and frequently occurring disease in orthopedics and traumatology, which brings heavy burden to patients, families and society. Waist and lower extremities is the most common symptoms of lumbar disc herniation. As for the pathogenesis of pain in lumbar intervertebral disc herniation ......
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