巴曲酶注射液治療全聾型突發(fā)性聾的臨床效果(1)
[摘要]目的 探討巴曲酶注射液治療全聾型突發(fā)性聾的臨床效果。方法 選取2015年1月～2019年10月我院收治的80例全聾型突發(fā)性聾患者作為研究對(duì)象，按照隨機(jī)數(shù)字表法將其分為觀察組和對(duì)照組，每組各40例。對(duì)照組患者采用用注射用甲潑尼龍琥珀酸鈉靜脈注射、銀杏葉提取物注射液靜脈滴注等常規(guī)治療方案，觀察組患者在對(duì)照組的基礎(chǔ)上加用巴曲酶注射液治療。治療前后進(jìn)行純音聽閾測(cè)試，比較兩組患者的療效，并分析聽力變化情況。結(jié)果 觀察組患者的顯效率為55.00%，總有效率為72.50%，對(duì)照組患者的顯效率為30.00%，總有效率為67.50%。觀察組患者的顯效率高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義(P<0.05);兩組患者的治療總有效率比較，差異無統(tǒng)計(jì)學(xué)意義(P>0.05);治療后，觀察組患者的低頻區(qū)平均聽閾和中頻區(qū)平均聽閾低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義(P<0.05);兩組患者的高頻區(qū)平均聽閾比較，差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論 巴曲酶注射液治療全聾型突發(fā)性聾有效，可以進(jìn)一步改善患者的聽力，對(duì)于中、低頻聽力的提高效果肯定，對(duì)高頻聽力的提高無明顯作用。
[關(guān)鍵詞]巴曲酶注射液;全聾型;突發(fā)性聾;臨床效果
[中圖分類號(hào)] R764.43 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-4721(2020)8(b)-0129-04
[Abstract] Objective To explore the clinical effect of Batroxobin Injection in the treatment of total deafness type sudden deafness. Methods A total of 80 patients with total deafness type sudden deafness who were hospitalized from January 2015 to October 2019 were selected as subjects and divided into the observation group and the control group according to the random number table method， with 40 cases in each group. Patients in the control group were treated by intravenous injection of Sodium Methylprednisolone Succinate and intravenous infusion of Extract of Ginkgo Biloba Injection. Patients in the observation group was treated by Batroxobin Injection on the basis of the control group. Pure tone audiometry was performed before and after treatment to compare the curative effect of the two groups and analyze the changes of hearing. Results The apparent efficiency of the observation group was 55.00%， the total effective rate was 72.50%. In the control group， the apparent efficiency was 30.00% and the total effective rate was 67.50%. The apparent efficiency in the observation group was higher than that of the control group， the difference was statistically significant (P<0.05). Comparison of the total effective rate between the two groups showed no statistically significant difference (P>0.05). After treatment， the average hearing threshold in the low-frequency and middle-frequency regions of the observation group were lower than those of the control group， with statistically significant differences (P<0.05). There was no statistically significant difference in the average hearing threshold between the two groups in the high-frequency region (P>0.05). Conclusion Batroxobin Injection was proved effective in the treatment of total deafness type sudden deafness， which could improve the hearing of patients in further. It has positive effect on the improvement of middle and low frequency hearing， but has no effect on the improvement of high frequency hearing., 百拇醫(yī)藥(馮瑋)
[關(guān)鍵詞]巴曲酶注射液;全聾型;突發(fā)性聾;臨床效果
[中圖分類號(hào)] R764.43 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-4721(2020)8(b)-0129-04
[Abstract] Objective To explore the clinical effect of Batroxobin Injection in the treatment of total deafness type sudden deafness. Methods A total of 80 patients with total deafness type sudden deafness who were hospitalized from January 2015 to October 2019 were selected as subjects and divided into the observation group and the control group according to the random number table method， with 40 cases in each group. Patients in the control group were treated by intravenous injection of Sodium Methylprednisolone Succinate and intravenous infusion of Extract of Ginkgo Biloba Injection. Patients in the observation group was treated by Batroxobin Injection on the basis of the control group. Pure tone audiometry was performed before and after treatment to compare the curative effect of the two groups and analyze the changes of hearing. Results The apparent efficiency of the observation group was 55.00%， the total effective rate was 72.50%. In the control group， the apparent efficiency was 30.00% and the total effective rate was 67.50%. The apparent efficiency in the observation group was higher than that of the control group， the difference was statistically significant (P<0.05). Comparison of the total effective rate between the two groups showed no statistically significant difference (P>0.05). After treatment， the average hearing threshold in the low-frequency and middle-frequency regions of the observation group were lower than those of the control group， with statistically significant differences (P<0.05). There was no statistically significant difference in the average hearing threshold between the two groups in the high-frequency region (P>0.05). Conclusion Batroxobin Injection was proved effective in the treatment of total deafness type sudden deafness， which could improve the hearing of patients in further. It has positive effect on the improvement of middle and low frequency hearing， but has no effect on the improvement of high frequency hearing., 百拇醫(yī)藥(馮瑋)